List of Famous people born in Prešov Region, Slovakia

Daniela Hantuchová is a retired Slovak tennis player and commentator. She turned professional in 1999 and had her breakthrough year in 2002, when she won her first WTA tournament, the Indian Wells Masters, defeating Martina Hingis in the final and becoming the lowest-ranked player to ever win the tournament. She also reached the quarterfinals of that year's Wimbledon Championships and US Open, ending the year in the top ten. She was part of the Slovak team that won the 2002 Fed Cup and the 2005 Hopman Cup.

Marián Hossa is a Slovak former professional ice hockey right winger.

Johann Breyer was a onetime SS-Totenkopfverbände concentration and death camp guard and retired tool and die maker whom the United States Department of Justice Office of Special Investigations (OSI) unsuccessfully attempted to denaturalize and deport for his teenage service in the SS. His was considered the "most arcane and convoluted litigation in OSI history", owing to the convergence of three unusual legal factors in the case:

• the question of whether the inability of American mothers to transmit citizenship to children born outside the U.S. before 1934 was unconstitutional,
• if so, then whether Breyer should be retroactively a U.S. citizen at birth and whether that citizenship was lost by volunteering to participate in SS activities,
  • and if so, then whether those activities or a later misrepresentation of his wartime activities to evade U.S. immigration law and enter the U.S. allowed for loss of his later-acquired citizenship, and
• his lawsuits against the media over coverage of the case.

Ondřej Duda is a Slovak professional footballer who plays as an attacking midfielder for 1. FC Köln and the Slovakia national team.

Peter Rusnák is the current bishop of the Eparchy of Bratislava.

István Thomán was a Hungarian piano virtuoso and music educator. He was a notable piano teacher, with students including Béla Bartók, Ernő Dohnányi and Georges Cziffra. His six-volume Technique of Piano Playing is still in use today.

Ŝtephen Sečka was a Slovak Roman Catholic bishop.

Kristína Peláková, professionally known as Kristína, is a Slovak singer. She is best known for representing Slovakia in the Eurovision Song Contest 2010 with the song “Horehronie”. The song placed 16th in the semi-final with a total of 24 points. Kristína is one of the most popular female artists in Slovakia and the Czech Republic, and has toured both countries on multiple occasions.

Miroslav Lajčák is a Slovak politician and diplomat, former Minister of Foreign Affairs of the Slovak Republic. In addition, Lajčak also served as President of the United Nations General Assembly for the 72nd session from 2017 until 2018.

Marcel Palonder is a Slovak singer. He represented his country in the Eurovision Song Contest 1996 with the song "Kým nás máš". His song qualified from the semifinal, earning 36 points but in the final it placed 17th place with 19 points. The points to the Slovak entry were given by: Greece four points, Malta eight points, Poland five points and Spain two points.