List of Famous people born in North Aegean Region, Greece

Hippocrates of Chios was an ancient Greek mathematician, geometer, and astronomer.

Dorino Gattilusio was the fourth Gattilusio Lord of Lesbos from 1428 until his death. He ruled Lesbos at a time of increasing Ottoman power, and his last years were preoccupied with maintaining some measure of independence.

Theophrastus, a Greek native of Eresos in Lesbos, was the successor to Aristotle in the Peripatetic school. His given name was Tyrtamus (Τύρταμος); his nickname Θεόφραστος was given by Aristotle for his 'divine style of expression'.

Francesco II Gattilusio was the second Gattilusio lord of Lesbos, from 1384 to his death. He was the third son of Francesco I Gattilusio and Maria Palaiologina, the sister of the Byzantine emperor John V Palaiologos.

Palamede Gattilusio was the Lord of Ainos from 1409 to his death, succeeding his great-uncle Niccolò. He was a younger son of Francesco II of Lesbos.

Ahmet Rüstem Bey (1862–1934), born Alfred Bilinski, was an Ottoman diplomat who served as last Ottoman ambassador to the United States in 1914. Despite neither of his parents being ethnically Turkish, he himself was an ardent Turkish nationalist. He was "exceptionally high-strung and outspoken" and had a "propensity to challenge people to duels". Prior to his appointment as ambassador, he had already served twice in the United States capital, both times leaving in a hurry.

Marchese Vincenzo Giustiniani was an aristocratic Italian banker, art collector and intellectual of the late 16th and early 17th centuries, known today largely for the Giustiniani art collection, assembled at the Palazzo Giustiniani, near the Pantheon, in Rome, and at the family palazzo at Bassano by Vincenzo and his brother, Cardinal Benedetto, and for his patronage of the artist Caravaggio.

Vincenzo Giustiniani was an Italian-Greek Dominican friar of Genoese heritage.

Kostas Vaxevanis is a Greek journalist. He is the owner and editor of the magazine Hot Doc and newspaper Documento.