List of Famous people born in Crete Region, Greece

Ioanna "Nana" Mouskouri is a Greek singer. Over the span of her career, she has released over 200 albums in at least twelve languages, including Greek, French, English, German, Dutch, Italian, Portuguese, Spanish, Hebrew, Welsh, Mandarin Chinese and Corsican.

John Anthony Aniston is a Greek-born American actor. He is best known for his role as Victor Kiriakis on the NBC daytime drama series Days of Our Lives, which he originated in July 1985 and has played continually since then. He is the father of Jennifer Aniston.

Ioannis Ikonomou is a Greek translator who has been working for the European Commission in Brussels since 2002. Considered a notable contemporary example of a polyglot, he knows 32 living languages including Greek, English, German, Italian, Spanish, French, Finnish, Danish, Russian, Swahili, Hebrew, Arabic, Mandarin and Bengali, and reportedly as many as 47 languages including dead languages like Old Church Slavic. He speaks 21 out of 24 official EU languages. He considers the Mandarin language as the most complicated language to learn. Chinese is also his favorite language. He is the only in-house translator of the European Commission who is trusted to translate classified Chinese documents.

Doménikos Theotokópoulos, most widely known as El Greco, was a Greek painter, sculptor and architect of the Spanish Renaissance. "El Greco" was a nickname, a reference to his Greek origin, and the artist normally signed his paintings with his full birth name in Greek letters, Δομήνικος Θεοτοκόπουλος, Doménikos Theotokópoulos, often adding the word Κρής Krēs, Cretan.

Cevat Şakir Kabaağaçlı was a Turkish writer of novels, short-stories and essays, as well as being a keen ethnographer and travelogue.

Konstantinos Mitsotakis was a Greek politician who was Prime Minister of Greece from 1990 to 1993. He graduated in law and economics from the University of Athens. His son, Kyriakos Mitsotakis, was elected as the Prime Minister of Greece following the 2019 Greek legislative election.

Giorgos Giakoumakis is a Greek professional footballer who plays as a striker for Scottish Premiership club Celtic and the Greece national team.

Nikos Kazantzakis was a Greek writer. Widely considered a giant of modern Greek literature, he was nominated for the Nobel Prize in Literature in nine different years.

Georgios Kalaitzakis is a Greek professional basketball player for the Milwaukee Bucks of the National Basketball Association (NBA). At a height of 2.03 m (6'8") tall and a weight of 93 kg (205 lbs.), he can play as a combo guard, and he can also operate as a point forward. As a youth, Kalaitzakis was regarded as one of the top young prospects in Europe, in his age range.

Nikolaos Andreas Dandolos, commonly known as Nick the Greek, was a Greek professional gambler and high roller.