List of Famous people born in Al Madinah Region, Saudi Arabia

Muhammad ibn Ali ibn Abi Talib also known as Muhammad ibn al-Hanafiyyah and surnamed Abu'l-Qasim. He was the third son of Ali ibn Abi Talib, the fourth Caliph of the Sunni Muslims, and the first Imam of the Shia Muslims.

Abū Saʿīd b. Abi ’l-Ḥasan Yasār al-Baṣrī, often referred to as Ḥasan of Basra for short, or reverentially as Imam Ḥasan al-Baṣrī in Sunni Islam, was an early Muslim preacher, ascetic, theologian, exegete, scholar, judge, and mystic. Born in Medina in 642, Hasan belonged to the second generation of Muslims, all of whom would subsequently be referred to as the tābiʿūn in Sunni Islamic piety. In fact, Hasan rose to become one of "the most celebrated" of the tābiʿūn, enjoying an "acclaimed scholarly career and an even more remarkable posthumous legacy in Islamic scholarship."

Jabir ibn Abdullah ibn Amr ibn Haram al-Ansari was a prominent companion of the Islamic prophet Muhammad.

Sa‘id Ibn Al-Musayyib of Medina was among the foremost authorities in jurisprudence (fiqh) among the Taba'een.

Muhammad ibn Abi Bakr was the Youngest son of Abu Bakr. He was not a companion of the Islamic prophet Muhammad but a Tabi'un. His mother was Asma bint Umays, who was a widow of Ja'far ibn Abi Talib prior to her second marriage with Abu Bakr. He became the adopted son of Ali, the fourth Rashidun Caliph and the first Imam of Shia Muslims, and became one of his generals.

Abū Dujāna Simāk bin Kharasha was a companion of Muhammad and a skilled swordsman who is mentioned in Hadith narrations from the six major Hadith collections of Sunni Islam.

Zaynab al-Sughra, also known by her kunya Umm Kulthum bint Ali, was the granddaughter of the Islamic prophet Muhammad and the daughter of Ali. Whether or not she married Umar is a controversial topic between Sunnis and Shia. She is given the epithet 'the Younger' to distinguish her from her older sister, Zaynab the Elder.

ʿAbd Allāh ibn 'Ubayy ibn Salūl, died 631, was a chieftain of the Khazraj tribe of Medina. Upon the arrival of the Islamic prophet Muhammad, Ibn Ubayy seemingly became a Muslim, but Muslim tradition says that he remained treacherous to Islam until his death. Because of repeated conflicts with Muhammad, Islamic tradition has labelled him a Munafiq (hypocrite) and "leader of the Munafiqun".

Ka'b ibn al-Ashraf was, according Islamic texts, a Jewish leader and poet in Medina. He was killed on the order of the Islamic prophet Muhammad after the Battle of Badr.

Ṣafwān ibn al-Muʿaṭṭal al-Sulamī was a sahabi (companion) of the Islamic prophet Muhammad and an Arab commander in the Muslim conquests. He was one of the first members of the Banu Sulaym to embrace Islam. He was accused, allegedly by the poet Abd-Allah ibn Ubayy, of having an affair with Muhammad's wife Aisha after the two became separated from a Medina-bound caravan. Later, Safwan became a commander and moved from Medina to Basra during the Muslim conquest of that region. Afterward, he took part in the military campaigns against the Byzantines in al-Jazira and Armenia, where he is said to have been slain. However, other reports mention that he died decades later as governor of Armenia.