List of Famous people born in Adelaide, Australia

Howard Walter Florey, Baron Florey of Adelaide and Marston was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin.

Darren Cahill is a tennis coach and former professional tennis player from Australia. In addition, Cahill is a tennis analyst for the Grand Slam events on the US sports network ESPN and a coach with the Adidas Player Development Program and at ProTennisCoach.com.

Nicholas Xenophon is an Australian politician and lawyer who was a Senator for South Australia from 2008 to 2017. He was the leader of two political parties: Nick Xenophon Team federally, and Nick Xenophon's SA-BEST in South Australia. In October 2017, Xenophon resigned from the Australian Senate to contest a seat in the House of Assembly at the 2018 South Australian state election. From 1997 to 2007, he was a member of the South Australian Legislative Council, serving as an independent on a No Pokies policy platform. When the Nick Xenophon Team changed its name to Centre Alliance, Xenophon himself ceased to be directly involved with the party.

Lionel George Logue, CVO, was an Australian speech and language therapist and amateur stage actor who helped King George VI manage his stammer.

Desmond Robert "Bill" Leak was an Australian editorial cartoonist, caricaturist and portraitist.

Paul Maurice Kelly is an Australian rock music singer-songwriter and guitarist. He has performed solo, and has led numerous groups, including the Dots, the Coloured Girls, and the Messengers. He has worked with other artists and groups, including associated projects Professor Ratbaggy and Stardust Five. Kelly's music style has ranged from bluegrass to studio-oriented dub reggae, but his core output straddles folk, rock, and country. His lyrics capture the vastness of the culture and landscape of Australia by chronicling life about him for over 30 years. David Fricke from Rolling Stone calls Kelly "one of the finest songwriters I have ever heard, Australian or otherwise." Kelly has said, "Song writing is mysterious to me. I still feel like a total beginner. I don't feel like I have got it nailed yet".

Orianthi Penny Panagaris is an Australian musician, singer and songwriter who rehearsed in 2009 with Michael Jackson in preparation for his ill-fated This Is It concert series, and performed with Alice Cooper's touring band. Her 2009 debut single "According to You" peaked at No. 3 in Japan, No. 8 in Australia and No. 17 in the US; her second album, Believe, received a worldwide release in late 2009. The same year, Orianthi was named one of the 12 Greatest Female Electric Guitarists by Elle magazine. She also won the "2010 Breakthrough Guitarist of the Year" award hosted by Guitar International magazine.

Peter Carter was an Australian tennis player and coach. He is widely known as the first and most influential coach of Roger Federer.

Sarah Snook is an Australian actress. She is known for her starring roles in many films, including Sisters of War (2010), Not Suitable for Children (2012), These Final Hours (2013), Predestination (2014), The Dressmaker (2015), Steve Jobs (2015), and Pieces of a Woman (2020). For her performance in Predestination, she won the AACTA Award for Best Actress in a Leading Role.

Bradford Leigh "Brad" Robinson was an Australian rock musician best known as lead and rhythm guitarist with the 1980s band Australian Crawl. He had a later career as a manager for musicians and sports personalities.