List of Famous people with last name O-brien

Rebecca O'Brien is a BAFTA-winning film producer, known especially for her work with Ken Loach. O'Brien was born in London, England.

Robert David O'Brien was an American football quarterback. He played college football at Texas Christian University (TCU) and professionally in the National Football League (NFL) with the Philadelphia Eagles for two seasons.

William Joseph Patrick O'Brien was an American film actor with more than 100 screen credits. Of Irish descent, he often played Irish and Irish-American characters and was referred to as "Hollywood's Irishman in Residence" in the press. One of the best-known screen actors of the 1930s and 1940s, he played priests, cops, military figures, pilots, and reporters. He is especially well-remembered for his roles in Knute Rockne, All American (1940), Angels with Dirty Faces (1938), and Some Like It Hot (1959). He was frequently paired onscreen with Hollywood legend James Cagney. O'Brien also appeared on stage and television.