List of Famous people born in Southern District, Israel

Antiochus of Ascalon was an Academic philosopher. He was a pupil of Philo of Larissa at the Academy, but he diverged from the Academic skepticism of Philo and his predecessors. He was a teacher of Cicero, and the first of a new breed of eclectics among the Platonists; he endeavoured to bring the doctrines of the Stoics and the Peripatetics into Platonism, and stated, in opposition to Philo, that the mind could distinguish true from false. In doing so, he claimed to be reviving the doctrines of the Old Academy. With him began the phase of philosophy known as Middle Platonism.

Eddie Butler is an Israeli singer. He was born in Dimona to a family of Black Hebrew Israelites from Chicago. Butler started performing at the age of eight. In the 1990s he sang with wedding bands, and in 1992 worked as a backing singer for Zehava Ben.

Avi Wortzman is an Israeli politician and a former member of the Knesset for the Jewish Home. He also served as Deputy Minister of Education between 2013 and 2014.

Haim Michael Revivo is a retired Israeli football player who played as a midfielder, and a businessman.

Amir Ohana is an Israeli lawyer, former Shin Bet official and politician who currently serves as Minister of Public Security. He previously held the post of Minister of Justice. He is the first openly gay right-wing member of the Knesset and the first openly gay man from Likud to serve in the Knesset. He is also the first openly gay person to be appointed as a minister in the Israeli government in 2019.