List of Famous people born in South Australia, Australia

Kyle Chalmers, is an Australian competitive swimmer who specialises in the sprint freestyle events. He is the Olympic champion in the 100 m freestyle and Vice World Champion in the 100 m freestyle.

Lachlan Neale is an Australian rules footballer playing for the Brisbane Lions in the Australian Football League (AFL). He previously played for the Fremantle Football Club from 2012 to 2018. He won the 2020 Brownlow Medal.

Adam Roy Goodes is a former professional Australian rules footballer who played for the Sydney Swans in the Australian Football League (AFL). Goodes holds an elite place in VFL/AFL history as a dual Brownlow Medallist, dual premiership player, four-time All-Australian, member of the Indigenous Team of the Century and representative of Australia in the International Rules Series. In addition, he has held the record for the most VFL/AFL games played by an Indigenous player, surpassing Andrew McLeod's record of 340 during the 2014 AFL season before having his own record surpassed by Shaun Burgoyne during the 2019 AFL season.

Howard Walter Florey, Baron Florey of Adelaide and Marston was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin.

Luke Saville is an Australian professional tennis player. As a junior, Saville enjoyed a successful career in which he won two junior grand slam singles titles at the 2011 Wimbledon Championships and 2012 Australian Open respectively. Saville is also a former junior World No. 1 and an Australian Institute of Sport scholarship holder. In January 2013, he competed in his first ATP main draw event at the 2013 Australian Open, but has struggled in transitioning from Juniors onto the professional circuit, reaching a highest singles ranking of only 152. However he has had greater success as a doubles player where he has reached his highest ranking of 37 in February 2020.

Darren Cahill is a tennis coach and former professional tennis player from Australia. In addition, Cahill is a tennis analyst for the Grand Slam events on the US sports network ESPN and a coach with the Adidas Player Development Program and at ProTennisCoach.com.

Kieran John Modra was an Australian Paralympic swimmer and tandem cyclist. He won five gold and five bronze medals at eight Paralympic Games from 1988 to 2016, along with two silver medals at the 2014 Glasgow Commonwealth Games.

Lionel Colin Matthews, was an Australian Army officer in World War II. He was posthumously awarded the George Cross, the highest award for heroism or courage not in the face of the enemy, that could be awarded to a member of the Australian armed forces at the time. Matthews was born in Adelaide, South Australia, and was schooled there before moving to Victoria. He trained as a signalman in the Royal Australian Naval Reserve before joining the Militia in April 1939. Commissioned as an officer in the Australian Corps of Signals, Matthews transferred to the 8th Division of the Second Australian Imperial Force after the outbreak of World War II.

Nicholas Xenophon is an Australian politician and lawyer who was a Senator for South Australia from 2008 to 2017. He was the leader of two political parties: Nick Xenophon Team federally, and Nick Xenophon's SA-BEST in South Australia. In October 2017, Xenophon resigned from the Australian Senate to contest a seat in the House of Assembly at the 2018 South Australian state election. From 1997 to 2007, he was a member of the South Australian Legislative Council, serving as an independent on a No Pokies policy platform. When the Nick Xenophon Team changed its name to Centre Alliance, Xenophon himself ceased to be directly involved with the party.

Paul Maurice Kelly is an Australian rock music singer-songwriter and guitarist. He has performed solo, and has led numerous groups, including the Dots, the Coloured Girls, and the Messengers. He has worked with other artists and groups, including associated projects Professor Ratbaggy and Stardust Five. Kelly's music style has ranged from bluegrass to studio-oriented dub reggae, but his core output straddles folk, rock, and country. His lyrics capture the vastness of the culture and landscape of Australia by chronicling life about him for over 30 years. David Fricke from Rolling Stone calls Kelly "one of the finest songwriters I have ever heard, Australian or otherwise." Kelly has said, "Song writing is mysterious to me. I still feel like a total beginner. I don't feel like I have got it nailed yet".