List of Famous people born in Pennsylvania, United States of America

Thomas Midgley Jr. was an American mechanical and chemical engineer. He played a major role in developing leaded gasoline (Tetraethyllead) and some of the first chlorofluorocarbons (CFCs), better known in the USA by the brand name Freon; both products were later banned due to concerns about their impact on human health and the environment. He was granted more than 100 patents over the course of his career.

James Joseph Croce was an American folk and rock singer-songwriter. Between 1966 and 1973, Croce released five studio albums and numerous singles.

John Corabi is an American hard rock singer and guitarist. He was the frontman of The Scream during 1989. He was also the frontman of Mötley Crüe between 1992 and 1996 during original frontman Vince Neil's hiatus from the band.

Seth Benjamin Green is an American actor, voice artist, comedian, producer, writer, and director. He is known as a co-creator, executive producer, and most frequent voice on Adult Swim's Robot Chicken and has also directed the Robot Chicken Star Wars and DC Comics specials.

Charles M. Lieber is an American chemist and pioneer in nanoscience and nanotechnology. In 2011, Lieber was named by Thomson Reuters as the leading chemist in the world for the decade 2000-2010 based on the impact of his scientific publications. He is known for his contributions to the synthesis, assembly and characterization of nanoscale materials and nanodevices, the application of nanoelectronic devices in biology, and as a mentor to numerous leaders in nanoscience.

Dion Waiters is an American professional basketball player who last played for the Los Angeles Lakers of the National Basketball Association (NBA). He played college basketball for the Syracuse Orange and was selected with the fourth overall pick in the 2012 NBA draft by the Cleveland Cavaliers. Waiters also played for the Oklahoma City Thunder, Miami Heat, and the Los Angeles Lakers, where he won an NBA championship.

Charles Hirsch Barris was an American game show creator, producer, and host. Barris was known for hosting The Gong Show and creating The Dating Game and The Newlywed Game. He was also a songwriter who wrote "Palisades Park" recorded by Freddy Cannon. Barris wrote an autobiography titled Confessions of a Dangerous Mind, which was made into the film of the same name and directed by George Clooney.

Lauren Michael Holly is an American-Canadian actress. She has played the roles of Deputy Sheriff Maxine Stewart in the television series Picket Fences, Director Jenny Shepard in the series NCIS, Dr. Betty Rogers on Motive, Mary Swanson in Dumb and Dumber, Linda Lee in Dragon: The Bruce Lee Story, Darian Smalls in Beautiful Girls, Cindy Rooney in Any Given Sunday, and Gigi in What Women Want.

Todd Andrew Howard is an American video game designer, director, and producer. He serves as director and executive producer at Bethesda Game Studios, where he has led the development of the Fallout and The Elder Scrolls series.

Denniston Oliver Moore Jr. is an American football wide receiver for the Carolina Panthers of the National Football League (NFL). He played college football at Maryland and was drafted by the Panthers in the first round of the 2018 NFL Draft.