List of Famous people born in Guayas Province, Ecuador

Enrique Raymondi is an Ecuadorian footballer. He played in five matches for the Ecuador national football team in 1963, scoring three goals. He was also part of Ecuador's squad for the 1963 South American Championship.

Carlos Xavier Rabascall Salazar is an Ecuadorian journalist, commercial engineer, businessman, and political consultant. In 2017, he was a member of the Front for Transparency and the Fight Against Corruption, a body in charge of proposing policies to prevent corruption in the public and private sectors. In December 2020, it was confirmed that he was part of the Union for Hope coalition together with Andrés Arauz, in the Ecuadorian presidential elections.

Gerardo Mejía, better known by his mononym Gerardo, is an Ecuadorian-American rapper, singer and actor who later became a recording industry executive, and more recently a pastor. Born in Guayaquil, Ecuador, he moved with his family to Glendale, California, when he was 12 years old.